รศ.ดร. เดภิชา จินดาทิพย์

รศ.ดร. เดภิชา จินดาทิพย์        

Depicha Jindatip, Ph.D.

Associate Professor

ข้อมูลการติดต่อ / Contact Information

ห้อง 1143 อาคารแพทยพัฒน์ ชั้น 11 ภาควิชากายวิภาคสตร์

เบอร์โทรศัพท์ภายใน: 02-256-4281 ต่อ 1710

Email: depicha.j@chula.ac.th

การศึกษา / Education

2005: B.Sc. Physical Therapy, (2nd Class Honours), Chulalongkorn University, Thailand                            

2007: M.Sc. Medical Science program in Anatomy, Chulalongkorn University, Thailand

2013: Ph.D. Histology and Cell Biology, Jichi Medical University School of Medicine, Japan

2014 to present:

– Lecturer: Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Thailand

– Visiting researcher: Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Japan

งานวิจัยที่สนใจ/ Research Interests

Pericytes in endocrine organs, Perivascular cells and extracellular matrix in pituitary gland, 3D reconstruction of cells and tissues

Appointments

Assistant Dean for Student Affairs of Faculty of Medicine 2562-2568                                                                                               

Chulalongkorn University, Bangkok, Thailand
Assistant Professor (Lecturer) of Anatomy and Histology 2561-2568

Department of Anatomy, Faculty of Medicine,                                                         

Chulalongkorn University, Bangkok, Thailand
Associate Professor (Lecturer) of Anatomy and Histology pres.

Department of Anatomy, Faculty of Medicine,                                                                       
Chulalongkorn University, Bangkok, Thailand
Visiting researcher pres.                   

Jichi Medical University School of Medicine, Tochigi, Japan                                                    
                              

Work Experiences

International lecture and workshop of transmission and scanning electron microscopies                   2012

for exchange students from Mahidol University

Jichi Medical University School of Medicine, Tochigi, Japan

International lecture and workshop of scanning electron microscopy                                                2011     for exchange students from Health Sciences University of Mongolia

Jichi Medical University School of Medicine, Tochigi, Japan

International lecture and workshop of transmission and scanning electron microscopies                   2010

for exchange students from Mahidol University

Jichi Medical University School of Medicine, Tochigi, Japan

The First Mongolian-Japanese International Workshop on Immunohistochemistry                           2009

            Health Sciences University of Mongolia, Ulaanbaatar, Mongolia         

 
Scholarships           
 
Jichi Medical University Scholarship for Special Foreign Graduate Students 2009 – 2013
    A full-expense scholarship for doing Ph.D. study at Jichi Medical University 
    School of Medicine, Tochigi, Japan 
       
Publications (Scopus: https://www.scopus.com/authid/detail.uri?authorId=22034891800)
  1. Lertpeerapan P, Kanlayaprasit S, Thongkorn S, Kasitipradit K, Panjabud P, Songsritaya K, Jantheang T, Morita M, Akaike T, Hu VW, Jindatip D, Saeliw T, Sarachana T (2025) Sex-dependent epigenetic disruption of YY1 binding by prenatal BPA exposure downregulates Matr3 and alters Agap1 splicing in the offspring hippocampus. Biol Sex Differ 16:63
  2. Kasitipradit K, Thongkorn S, Kanlayaprasit S, Saeliw T, Lertpeerapan P, Panjabud P, Jindatip D, Hu VW, Kikkawa T, Osumi N, Sarachana T (2025) Sex-specific effects of prenatal bisphenol A exposure on transcriptome-interactome profiles of autism candidate genes in neural stem cells from offspring hippocampus. Sci Rep 22:2882
  3. Saeliw T, Kanlayaprasit S, Thongkorn S, Songsritaya K, Sanannam B, Jindatip D, Hu VW, Sarachana T (2024) Investigation of chimeric transcripts derived from LINE-1 and Alu retrotransposons in cerebellar tissues of individuals with autism spectrum disorder (ASD). Sci Rep 19:21889
  4. Kanlayaprasit S, Saeliw T, Thongkorn S, Panjabud P, Kasitipradit K, Lertpeerapan P, Songsritaya K, Yuwattana W, Jantheang T, Jindatip D, Hu VW, Kikkawa T, Osumi N, Sarachana T (2024) Sex-specific impacts of prenatal bisphenol A exposure on genes associated with cortical development, social behaviors, and autism in the offspring’s prefrontal cortex. Biol Sex Differ 15:40
  5. Phoyen S, Sanpavat A, Ma-On C, Stein U, Hirankarn N, Tangkijvanich P, Jindatip D, Whongsiri P, Boonla C (2024) H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma. Heliyon. 20:e22589
  6. Likidkarnchanakornkij J, Jindatip D, Wannaprasert T (2023) Morphology of the digestive system of the lesser bamboo rat (Cannomys badius). Anat Histol Embryol 52:944-955
  7. Saeliw T, Kanlayaprasit S, Thongkorn S, Songsritaya K, Sanannam B, Sae-Lee C, Jindatip D, Hu VW, Sarachana T (2023)Epigenetic Gene-Regulatory Loci in Alu Elements Associated with Autism Susceptibility in the Prefrontal Cortex of ASD. Int J Mol Sci 19:7518
  8. Thongkorn S, Kanlayaprasit S, Kasitipradit K, Lertpeerapan P, Panjabud P, Hu VW, Jindatip D, Sarachana T (2023) Investigation of autism-related transcription factors underlying sex differences in the effects of bisphenol A on transcriptome profiles and synaptogenesis in the offspring hippocampus. Biol Sex Differ 20:8
  9. Kobutree P, Tothonglor A, Roumwong A, Jindatip D, Agthong S (2023) Curcumin reduces blood-nerve barrier abnormalities and cytotoxicity to endothelial cells and pericytes induced by cisplatin. Folia Morphol (Warsz) 82:533-542
  10. Wannaprasert T, Tabtimsri T, Jindatip, D (2023) Microanatomy and Spatial Distribution of the Tongue Musculature of the Lesser Bamboo Rat (Cannomys badius). Trop Nat Hist 23: 34-41 
  11. Tothonglor A, Kobutree P, Roumwong A, Jindatip D, Agthong S (2023) Cisplatin-induced alterations in the blood-nerve barrier: effects of combination of vitamin B1, B6 and B12. Folia Morphol (Warsz) 82:53-62
  12. Ariyachet C, Chuaypen N, Kaewsapsak P, Chantaravisoot N, Jindatip D, Potikanond S, Tangkijvanich P (2022) MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury. Int J Mol Sci. 2022 Aug 19;23(16):9380
  13. Yasom S, Watcharanurak P, Bhummaphan N, Thongsroy J, Puttipanyalears C, Settayanon S, Chalertpet K, Khumsri W, Kongkaew A, Patchsung M, Siriwattanakankul C, Pongpanich M, Pin-On P, Jindatip D, Wanotayan R, Odton M, Supasai S, Oo TT, Arunsak B, Pratchayasakul W, Chattipakorn N, Chattipakorn S, Mutirangura A (2022) The roles of HMGB1-produced DNA gaps in DNA protection and aging biomarker reversal. FASEB Bioadv 28:408-434
  14. Lordumrongkiat N, Chotechuang N, Prasanth MI, Jindatip D, Ma-On C, Chuenwisad K, Leelahavanichkul A, Tencomnao T, Boonla C (2022) HydroZitLa inhibits calcium oxalate stone formation in nephrolithic rats and promotes longevity in nematode Caenorhabditis elegans. Sci Rep 24:5102
  15. Kanlayaprasit S, Thongkorn S, Panjabud P, Jindatip D, Hu VW, Kikkawa T, Osumi N, Sarachana T (2021) Autism-Related Transcription Factors Underlying the Sex-Specific Effects of Prenatal Bisphenol A Exposure on Transcriptome-Interactome Profiles in the Offspring Prefrontal Cortex. Int J Mol Sci 22:13201
  16. Sanannam B, Looprasertkul S, Kanlayaprasit S, Kitkumthorn N, Sarachana T, Jindatip D (2021) Alteration of Extracellular Matrix Components in the Anterior Pituitary Gland of Neonatal Rats Induced by a Maternal Bisphenol A Diet during Pregnancy. Int J Mol Sci 22:12667
  17. Jindatip D, Poh RW, Fujiwara K (2021) Insight into the Characteristics of Novel Desmin-Immunopositive Perivascular Cells of the Anterior Pituitary Gland Using Transmission and Focused Ion Beam Scanning Electron Microscopy. Int J Mol Sci 22:8630
  18. Duangpakdee A, Laomeephol C, Jindatip D, Thongnuek P, Ratanavaraporn J, Damrongsakkul S (2021) Crosslinked Silk Fibroin/Gelatin/Hyaluronan Blends as Scaffolds for Cell-Based Tissue Engineering. Molecules 26:3191
  19. Looprasertkul S, Sereemaspun A, Kitkumthorn N, Sooklert K, Sarachana T, Jindatip D (2021) Gold Nanoparticles Affect Pericyte Biology and Capillary Tube Formation. Pharmaceutics 13:738
  20. Thongkorn S, Kanlayaprasit S, Panjabud P, Saeliw T, Jantheang T, Kasitipradit K, Sarobol S, Jindatip D, Hu VW, Tencomnao T, Kikkawa T, Sato T, Osumi N, Sarachana T (2021) Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions. Sci Rep 11:1241
  21. Sooklert K, Wongjarupong A, Cherdchom S, Wongjarupong N, Jindatip D, Yupa Phungnoi Y, Rojanathanes R, Sereemaspun A(2019) Molecular and morphological evidence of hepatotoxicity after silver nanoparticle exposure: a systematic review, in silico, and ultrastructure investigation. Toxicol Res 35:257−270
  22. Sooklert K, Nilyai S, Rojanathanes R, Jindatip D, Sae-Liang N, Kitkumthorn N, Mutirangura A, Sereemaspun A (2019) N-acetylcysteine reverses the decrease of DNA methylation status caused by engineered gold, silicon, and chitosan nanoparticles. Int J Nanomedicine 14:4573-4587
  23. Jindatip D, Nopparat W, Kobutree P, Roumwong A, Agthong S (2019) Pericyte loss and detachment in experimental cisplatin-induced neuropathy. Int J Morphol 37:509-514
  24. Thongkorn S, Kanlayaprasit S, Jindatip D, Tencomnao T, Hu VW, Sarachana T (2019) Sex differences in the effects of prenatal bisphenol A exposure on genes associated with autism spectrum disorder in the hippocampus. Sci Rep 9:3038
  25. Wannaprasert T, Phanthuma-opas P, Jindatip D (2019) Morphology and microstructure of the tongue of the lesser bamboo rat (Cannomys badius). Acta Zoologica (Article in Press) DOI: 10.1111/azo.12293
  26. Whongsiri P, Pimratana C, Wijitsettakul U, Sanpavat A, Jindatip D, Hoffmann MJ, Goering W, Schulz WA, Boonla C (2019)Oxidative stress and LINE-1 reactivation in bladder cancer are epigenetically linked through active chromatin formation. Free Radic Biol Med 134:419-428
  27. Azuma M, Tsukada T, Inagaki T, Casmad F, Jindatip D, Tofrizal A, Maliza R, Batchuluun K, Syaidah R, Ohno N, Fujiwara K, Kikuchi M, Yashiro T (2018) Immunohistochemical study of the laminin α5 chain and its specific receptor, basal cell adhesion molecule (bcam), in both fetal and adult rat pituitary glands. Acta Histochem Cytochem 51:145-152
  28. Whongsiri P, Pimratana C, Wijitsettakul U, Jindatip D, Sanpavat A, Schulz WA, Hoffmann MJ, Goering W, Boonla C (2018) LINE-1 ORF1 Protein Is Up-regulated by Reactive Oxygen Species and Associated with Bladder Urothelial Carcinoma Progression. Cancer Genomics Proteomics 15:143-151
  29. Jindatip D, Fujiwara K, Sarachana T, Mutirangura A, Yashiro T (2018) Characteristics of pericytes in diethylstilbestrol (DES)-induced pituitary prolactinoma in rats. Med Mol Morphol 51:147-155
  30. Tofrizal A, Fujiwara K, Azuma M, Kikuchi M, Jindatip D, Yashiro T, Yamada S (2017) Tissue inhibitors of metalloproteinase-expressing cells in human anterior pituitary and pituitary adenoma. Med Mol Morphol 50:145-154
  31. Fujiwara K, Yatabe M, Tofrizal A, Jindatip D, Yashiro T, Nagai R (2017) Identification of M2 macrophages in anterior pituitary glands of normal rats and rats with estrogen-induced prolactinoma. Cell Tissue Res 368:371-378
  32. Sooklert K, Chattong S, Manotham K, Boonwong C, Klaharn IY, Jindatip D, Sereemaspun A (2016) Cytoprotective effect of glutaraldehyde erythropoietin on HEK293 kidney cells after silver nanoparticle exposure. Int J Nanomedicine 11:597-605
  33. Jindatip D, Fujiwara K, Horiguchi K, Tsukada T, Kouki T, Yashiro T (2013) Changes in fine structure of pericytes and novel desmin-immunopositive perivascular cells during postnatal development in rat anterior pituitary gland. Anat Sci Int 88:196-203
  34. Horiguchi K, Syaidah R, Fujiwara K, Tsukada T, Ramadhani D, Jindatip D, Kikuchi M, Yashiro T (2013) Expression of the cell-surface heparan sulfate proteoglycan syndecan-2 in developing rat anterior pituitary gland. Cell Tissue Res 353:473-81
  35. Horiguchi K, Syaidah R, Fujiwara K, Tsukada T, Ramadhani D, Jindatip D, Kikuchi M, Yashiro T (2013) Expression of small leucine-rich proteoglycans in rat anterior pituitary gland. Cell Tissue Res 351:207-212
  36. Jindatip D, Fujiwara K, Kouki T, Yashiro T (2012) Transmission and scanning electron microscopic study of the characteristics and morphology of pericytes and novel desmin immunopositive perivascular cells before and after castration in rat anterior pituitary gland. Anat Sci Int 87:165-173
  37. Fujiwara K, Jindatip D, Kikuchi M, Yashiro T (2010) In situ hybridization reveals that type I and III collagens are produced by pericytes in the anterior pituitary gland of rats. Cell Tissue Res 342:491-495
  38. Tansatit T, Kulvitit Y, Jindatip D (2006) Comparison of economic bipolar vessel sealer and biclamp for the hemostasis of large-sized cadaver arteries. J Med Assoc Thai 89 Suppl 3:S169-73

Invited speaker

  1. Morphology and characteristics of pericytes and novel desmin-immunopositive perivascular cells in rat hypophysis. The 6thChula Neuroscience forum 2014 (Bangkok, Thailand: March 22, 2014)
  2. Current State of Anatomy Education and Research at Soft Cadaver Surgical Training Center of Chulalongkorn University, Thailand. The 119th Annual Meeting of the Japanese Association of Anatomists (Tochigi, Japan: March 26, 2014)
  3. Pericyte and Novel Cellular Regulation of Pituitary Gland. The 53rd CU med conference (Bangkok, Thailand: June 17, 2014) 
  4. Lecture for satellite meeting: Morphological analyses of pituitary pericytes and desmin-immunopositive perivascular (DIP) cells in normal and prolactinoma rats. The 121st Annual Meeting of the Japanese Association of Anatomists (Fukushima, Japan: March 28, 2016)
  5. Focused ion beam scanning electron microscopy revealed three-dimensional fine structure of the cells. The 11th Asia-Pacific Microscopy Conference, the 33rd Annual Conference of the Microscopy Society of Thailand, and the 9th Annual Conference of the Anatomy Association of Thailand join conference (Phuket, Thailand: May 25, 2016)

Oral presentations

  1. Depicha Jindatip, Ken Fujiwara, Megumi Yatabe, Takashi Yashiro. Morphological analysis of pericytes in anterior pituitary glands of normal and castrated rats. The 25th Annual Meeting of Japan Society for Pituitary Research (Aichi, Japan: August 20, 2010)
  2. Depicha Jindatip, Ken Fujiwara, Megumi Yatabe, Tom Kouki, Takashi Yashiro. Morphological study of pericytes in rat anterior pituitary glands. The 14th Annual Meeting of the Japan Endocrine Pathology Society (Kyoto, Japan: October 29, 2010)
  3. Depicha Jindatip, Ken Fujiwara, Tom Kouki, Megumi Yatabe, Takashi Yashiro. Identification of pericytes in the rat anterior pituitary gland. The 88th Annual Meeting of The Physiological Society of Japan and the 116th Annual Meeting of the Japanese Association of Anatomists join conference (Yokohama, Japan:  March 29, 2011)
  4. Depicha Jindatip, Ken Fujiwara, Tom Kouki, Takashi Yashiro. Castration induces morphological changes of pericytes in rat anterior pituitary gland. The 26th Annual Meeting of Japan Society for Pituitary Research (Okayama, Japan: August 26, 2011)
  5. Depicha Jindatip, Ken Fujiwara, Tom Kouki, Takashi Yashiro. Electron microscopic analyses of pericytes in rat anterior pituitary gland. The 38th Annual Meeting of Japan Neuroendocrine Society (Tokyo, Japan: November 25, 2011)
  6. Depicha Jindatip, Ken Fujiwara, Tom Kouki, Megumi Yatabe, Floren Ly, Takashi Yashiro. Morphological characteristics of pericytes and new desmin-immunopositive perivascular cells in the anterior pituitary gland of postnatal rats. The 27th Annual Meeting of Japan Society for Pituitary Research (Yamagata, Japan: August 9, 2012)
  7. Depicha Jindatip, Ken Fujiwara, Takashi Yashiro. Identification of two types of perivascular cells in the postnatal anterior pituitary gland, with special reference to their collagen synthesis. The 37th Annual Conference of the Anatomy Association of Thailand (Phitsanulok, Thailand: May 7, 2014)

Poster Presentations

  1. Depicha Jindatip, Ken Fujiwara, Tom Kouki, Takashi Yashiro. Identification of pericytes and their morphological changes in the anterior pituitary gland of castrated rat. The 10th Jichi Medical University Symposium (Tochigi, Japan: September 2, 2011)
  2. Depicha Jindatip, Ken Fujiwara, Takashi Yashiro. Characteristics of pericytes and novel desmin-immunopositive perivascular cells in rat anterior pituitary gland. The 2nd International Anatomical Sciences and Cell Biology Conference (Chiang Mai, Thailand: December 7, 2012)
  3. Depicha Jindatip, Tewarit Sarachana, Amornpun Sereemaspun. Changes in characteristics of pericytes in diethylstilbestrol (DES) -induced pituitary prolactinoma rats. The 121st Annual Meeting of the Japanese Association of Anatomists (Fukushima, Japan: March 29, 2016)
  4. Depicha Jindatip, Rebecca Poh. Three-dimensional morphology of novel desmin-immunopositive perivascular (DIP) cell in rat anterior pituitary gland by using FIB/SEM tomography. 19th International Microscopy Congress 2018 (Sydney, Australia: September 11, 2018)
Honors

Best presentation award in The 25th Japan Pituitary Research Conference, Irago, Japan, 2010

The winner in SEM photo contest at the 11th Asia-Pacific microscopy conference 2016

Cover figure of Anatomical Science International, Vol.88, 2013

The Research Award to JMU Graduate Student, Tochigi, Japan, 2012